A Performance-Portable SYCL Implementation of CRK-HACC for Exascale

The first generation of exascale systems will include a variety of machine architectures, featuring GPUs from multiple vendors. As a result, many developers are interested in adopting portable programming models to avoid maintaining multiple versions of their code. It is necessary to document experiences with such programming models to assist developers in understanding the advantages and disadvantages of different approaches. To this end, this paper evaluates the performance portability of a SYCL implementation of a large-scale cosmology application (CRK-HACC) running on GPUs from three different vendors: AMD, Intel, and NVIDIA. We detail the process of migrating the original code from CUDA to SYCL and show that specializing kernels for specific targets can greatly improve performance portability without significantly impacting programmer productivity. The SYCL version of CRK-HACC achieves a performance portability of 0.96 with a code divergence of almost 0, demonstrating that SYCL is a viable programming model for performance-portable applications.Comment: 12 pages, 13 figures, 2023 International Workshop on Performance, Portability & Productivity in HP

The insertion of China in the international garlic market. A descriptive analysis, 1960-2014

[ES] Este artículo analiza los cambios en el negocio mundial del ajo entre 1960 y 2014, abordando tanto la oferta mundial, concentrada en Asia especialmente desde la década de 1990, como la demanda, esta última, aunque también liderada por Asia, bastante más dispersa en términos geográficos, en consonancia con la mayor presencia en el comercio de importación de algunas economías europeas y americanas. En este contexto, España ha conseguido mantener su cuota en el mercado mundial, posicionándose en la actualidad como el segundo país exportador del mundo, solo por detrás de China.[EN] This article analyzes the changes in the global garlic business between 1960 and 2014, addressing both the global supply, concentrated in Asia especially since the 1990s, and the demand, the latter, although also led by Asia, much more dispersed in geographical terms, in line with the greater presence in the import trade of some European and American economies. In this context, Spain has managed to maintain its share in the world market, currently positioning itself as the second largest exporting country in the world, being surpassed only by China.Junta de Extremadura y fondos FEDER a través de la Ayuda a Grupos de Investigación Catalogados (GR18140).Parejo-Moruno, FM.; Rangel-Preciado, JF.; Cruz-Hidalgo, E. (2020). La inserción de China en el mercado internacional del ajo. Un análisis descriptivo, 1960-2014. Economía Agraria y Recursos Naturales - Agricultural and Resource Economics. 20(1):77-101. https://doi.org/10.7201/10.7201/earn.2020.01.04OJS7710120

The importance of secondary halos for strong lensing in massive galaxy clusters across redshift

Cosmological cluster-scale strong gravitational lensing probes the mass distribution of the dense cores of massive dark matter halos and the structures along the line of sight from background sources to the observer. It is frequently assumed that the primary lens mass dominates the lensing, with the contribution of secondary masses along the line of sight being neglected. Secondary mass structures may, however, affect both the detectability of strong lensing in a given survey and modify the properties of the lensing that is detected. This paper focuses on the former: we utilize a large cosmological N-body simulation and a multiple lens plane (and many source plane) ray-tracing technique to quantify the influence of line of sight structures on the detectability of cluster-scale strong lensing in a cluster sample with a mass limit that encompasses current cluster catalogs from the South Pole Telescope. We extract both primary and secondary halos from the "Outer Rim" simulation and consider two strong lensing realizations-one with only the primary halos included, and the other with the full mass light cone for each primary halo, including all secondary halos down to a mass limit more than an order of magnitude smaller than the smallest primary halos considered. In both cases, we use the same source information extracted from the Hubble Ultra Deep Field, and create realistic lensed images consistent with moderately deep ground-based imaging; the statistics of the observed strong lensing are extracted from these simulated images. The results demonstrate that down to the mass limit considered the total number of lenses is boosted by ∼ 13 − 21% when considering the complete multi-halo light-cone; the enhancement is insensitive to different length-to-width cuts applied to the lensed arcs. The increment in strong lens counts peaks at lens redshifts of z ∼ 0.6 with no significant effect at z < 0.3. The strongest trends are observed relative to the primary halo mass, with no significant effect in the most massive quintile of the halo sample, but increasingly boosting the observed lens counts toward small primary halo masses, with an enhancement greater than 50% in the least massive quintile of the halo masses considered

Clinical course of sepsis, severe sepsis, and septic shock in a cohort of infected patients from ten Colombian hospitals

ABSTARCT: Sepsis has several clinical stages, and mortality rates are different for each stage. Our goal was to establish the evolution and the determinants of the progression of clinical stages, from infection to septic shock, over the first week, as well as their relationship to 7-day and 28-day mortality

The Neural Basis of Decision-Making and Reward Processing in Adults with Euthymic Bipolar Disorder or Attention-Deficit/Hyperactivity Disorder (ADHD)

Attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) share DSM-IV criteria in adults and cause problems in decision-making. Nevertheless, no previous report has assessed a decision-making task that includes the examination of the neural correlates of reward and gambling in adults with ADHD and those with BD

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to &lt;90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], &gt;300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of &lt;15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P&lt;0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P&lt;0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years